Linear-Time Haplotype Inference on Pedigrees Without Recombinations

نویسندگان

  • Bethany Man-Yee Chan
  • Wun-Tat Chan
  • Francis Y. L. Chin
  • Stanley P. Y. Fung
  • Ming-Yang Kao
چکیده

In this paper, a linear-time algorithm, which is optimal, is presented to solve the haplotype inference problem for pedigree data when there are no recombinations and the pedigree has no mating loops. The approach is based on the use of graphs to capture SNP, Mendelian and parity constraints of the given pedigree.

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تاریخ انتشار 2006